What Does megatomi.com Mean?

Our new Crystal clear+ tissue clearing technique is the sole strategy that delipidates samples without improve in morphology and with minimal impact on structural integrity.

Megatome can be a vibrating microtome intended to part a wide range of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome allows large-throughput tissue sectioning with uniform area profile, and minimal tissue harm and data decline.

Antibodies may just take months to diffuse by means of only some millimeters of tissue, having a steep labeling gradient from floor to core.

Megatome is created for precision: the blade vibrates at a better frequency and larger amplitude assortment than other microtomes, and includes a special deflection Handle mechanism.

SE works by using a rotational electrical discipline to disperse extremely electromobile molecules (like antibodies or surfactant micelles) throughout a porous sample without the need of harming electrically billed constructions inside the tissue. This enables two-four day clearing of intact organs,

Our preformulated EasyIndex Resolution raises and homogenize the refractive index of delipidated tissue samples, rendering them completely clear. This enables light penetration to the sample and guarantees the acquisition of significant-resolution, in-emphasis picture data.

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eFLASH is usually a quick tissue labeling technique that enables for uniform entire-organ staining in twenty rounds of labeling.

Fully delipidate entire mouse brains or comparably sized samples in only one day with SmartBatch+, or in one week with our passive clearing kit.

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Defend avoids the variability of hydrogel embedding and the data loss megatomi.com from PFA preservation, defending specimens for many rounds of processing.

Leverage the Clear+ tissue clearing approach, as well as eFLASH and patented stochastic electrotransport systems, to rapidly distinct and label complete organs. Essential highlights and features include things like:

Our novel Protect tissue preservation approach forms intramolecular bonds making use of polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.

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